History of Carboplatin

How Carboplatin Was Developed

Building on the success of cisplatin, Dr. Barnett Rosenberg and his team at Michigan State University got to work developing a “second generation” drug. The result was carboplatin, which is a modified form of, and worked in largely the same way as, cisplatin. It is a chemotherapy drug that, like cisplatin, belongs to a group of drugs referred to as alkylating agents. The major difference was that it had fewer and less severe side effects.

Joining Dr. Rosenberg’s team on the carboplatin project were Dr. Michael J. Cleare from the Johnson Matthey Research Center in England and Dr. James D. Hoeschele from Michigan State University. Carboplatin was approved by the U.S. Food and Drug Administration (FDA) as an anticancer drug in 1989 and was initially marketed by Bristol-Myers Squibb under the brand name Paraplatin®.

After the expiration for the patent on carboplatin in 2004, a number of generic versions of the drug became available.

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Use the following links to learn more about carboplatin and its use in the battle against mesothelioma.

Always consult with your doctor and/or oncologist before beginning any chemotherapy treatment regimen.

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