The History of Cisplatin

Cisplatin, sometimes referred to as CDDP, is a platinum-based chemotherapy drug and is a member of a group of drugs known as alkylating agents. It was initially recognized as a compound by chemist M. Peyrone in 1845 and was known for many years as Peyrone's salt. In 1893, chemist Alfred Werner completed his research and published his findings on the chemical structure of cisplatin.

After later research showed that cisplatin inhibited cell division in bacteria, Dr. Barnett Rosenberg, a Michigan State University professor of chemistry, recognized its potential as a treatment for cancer. Following extensive research and development during the mid-70s, cisplatin was approved by the U.S. Food and Drug Administration (FDA) as an anticancer drug in 1978 and was patented by the university in 1979.

Michigan State University made an agreement with Bristol-Myers Squibb to produce cisplatin, the company marketed the drug under the names Platinol® and Platinol-AQ®.

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Always consult with your doctor and/or oncologist before beginning any chemotherapy treatment regimen.

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